2022 Jul 6;15(1):9503. doi: 10.4081/dr.2022.9503. Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. -, Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI. Keywords: This is called a herald patch and may be up to 4 inches (10 centimeters) across. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination (2016) 55:e33843. J Eur Acad Dermatol Venereol. official website and that any information you provide is encrypted Urbina F, Das A, Sudy E. Clinical variants of pityriasis rosea. Available doctors, insurances and verified patient reviews for Optimized Health and Wellness. All patients were treated with cetirizine (20 mg/day for 7-14 days). Secukinumab for pityriasis rubra pilaris (December 2022) SKIN CANCER. sharing sensitive information, make sure youre on a federal Tina Burke, 40, a nurse who works on the oncology floor at Massachusetts General Hospital (MGH), received her first coronavirus shot on Jan. 3. Khan I, Elsanousi AA, Shareef AM, Tebha SS, Arif A, Gul S. Immun Inflamm Dis. Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. and the adverse cutaneous effects of COVID-19 . 18. Temiz SA, Abdelmaksoud A, Dursun R, et al.. Pityriasis rosea following SARSCoV- 2 vaccination: a case series. Please enable it to take advantage of the complete set of features! Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. J Eur Acad Dermatol Venereol. . Moreover, central dusky-red erythematous was observed on some plaques (Figure 2A). He described the appearance of an erythematous centrally scaled lesion at the right part of his abdomen, followed by the spreading of red oval mildly scaling lesions on the trunk, neck, and proximal parts of the upper extremities, which showed in the physical examination (Figure 1, a and b). MeSH Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Researchers Continue to Find Clues About MIS-C - Yale Medicine It is important for physicians to be aware of this self-limited reaction so they can reassure and appropriately counsel patients that it is safe to receive subsequent vaccine doses despite the cutaneous eruption. The site is secure. Bin Rubaian NF, Almuhaidib SR, Aljarri SA, Alamri AS. doi: 10.1016/j.jaad.20.2103.092. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). government site. We report 10 . JAAD Case Rep. (2018) 4:8001. doi: 10.1111/jdv.17342. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. 10.1007/S11356-020-12070-7 doi: 10.1111/dth.15040, 3. Pityriasis rosea and pityriasis rosea-like eruption after anti-SARS-CoV Veraldi S, Boneschi V, Cusini M, Maronese CA. The rash typically lasts 6-9 weeks, rarely extending longer than 12 weeks. National Library of Medicine Dermatol Ther. 2023 Apr;11(4):e804. Epub 2021 Jun 28. Changes in color or texture can result from inflammation, infection, or allergic reactions anywhere on the body. J Eur Acad Dermatol Venereol. Contributions: SV and CAM, conceived and wrote the article. J Med Virol. Please enable it to take advantage of the complete set of features! Most people with the rash are 10 to 35 years of age. In addition to COVID-19 vaccination, she was currently taking medications (i.e., levetiracetam and thyroxin) for glioblastoma, and the two drugs had been prescribed for approximately nine months. Manifestation of pityriasis rosea and pityriasis rosea-like eruptions See this image and copyright information in PMC. Reactivation of Herpes Zoster Virus After COVID-19 Vaccination: Is Dermatol Ther. Complete remission was observed within 14-30 days. Abdominal fullness prematurely after meals and Pityriasis rosea From the Cochrane Library: Interventions for Pityriasis Rosea Skin Reactions After COVID-19 Vaccination Have Six Patterns - Medscape Dursun R, Temiz SA. Efficacy and safety of COVID19 vaccines: a systematic review. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. 2022 May;35(5):e15391. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. Why covid arm and other post-vaccine rashes might actually be a 'good They are described as small, itchy blisters found on the trunk of the body and filling with blood, present in middle-aged patients. eCollection 2022 Jul. Central dusky-red erythematous on some plaques (A); almost all lesions fading with associated post-inflammatory hyperpigmentation after treatment (B). Table 1. 8600 Rockville Pike 17% get a rash first and then get other symptoms later on as disease progresses. doi: 10.1111/ijd.13061. The site is secure. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. -, Wollina U, Chiriac A, Kocic H, Koch A, Brzezinski P. Cutaneous and hypersensitivity reactions associated with COVID19 vaccinationa narrative review. Umakanthan S, Sahu P, Ranade AV, et al. Henry Ford Health Henry Ford Health Scholarly Commons -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. Conflict of interest: The authors declare no potential conflict of interest. Careers. Polack FP, Thomas SJ, Kitchin N, et al. However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). FOIA Several vaccines have been created to counteract the morbidity and mortality associated with COVID19 and stop viral transmission, including the Moderna vaccine (Mrna1273).The mRNA1273 vaccine is a lipid nanoparticle-encapsulated mRNAbased vaccine that encodes the prefusion stabilized fulllength spike . doi: 10.1111/ijd.15700, 4. doi: 10.1111/jdv.17342, 5. An official website of the United States government. Before The https:// ensures that you are connecting to the FOIA Bookshelf doi: 10.1002/iid3.804. These types cannot cause cold sores or genital herpes. Accessibility eCollection 2022. doi: 10.1111/bjd.20143. government site. The average age of incidence was calculated to be 44.92 years, and 63 (62.37%) people presented after administration of the first dose. Cutis. (2021) 35:e4913. JAAD Case Rep. 2021;7:9394. There is a growing number of published cases that link PR to COVID-19 infection, with PR appearing either in the acute phase of COVID-19 or, as in our patient, in the post COVID-19 period (4-9). Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. Epub 2022 Jun 13. Skin Diseases Associated With COVID-19: A Narrative Review Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. +39.3465909404. 2021;35(8):e489e491. eCollection 2021. Methods: Histopathologic features: (B) microscopic image at a low power field showing psoriasiform epidermal hyperplasia, perivascular infiltration, and interface dermatitis (hematoxylin-eosin; scale bar represents 100 m); (C) microscopic image at a high power field showing focal spongiotic dermatitis, interface dermatitis, and perivascular infiltration of lymphocytes and eosinophils (hematoxylin-eosin; scale bar represents 40 m). 2021 Nov;34(6):e15129. Bookshelf Drago F, Ciccarese G, Javor S, Parodi A. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. It is usually seen in children, adolescents, and young adults. The mechanisms behind these COVID-19-related symptoms remain unclear. Epub 2022 Jan 31. Manifestation of pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccine: A systematic review. How Does A Person Get Pityriasis Rosea? - eMedicineHealth J Eur Acad Dermatol Venereol. (2006) 12:1. doi: 10.5070/D380D8301D, 11. However, pityriasis rosea is a selflimiting benign exanthema and does not require . Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. (2019) 34:185764. New urticaria in the weeks after COVID-19 vaccination (March 2023) OTHER DERMATOLOGY. Copyright 2021 Leerunyakul, Pakornphadungsit and Suchonwanit. Accessibility doi: 10.1159/000517971. Would you like email updates of new search results? Careers. Pityriasis rosea after mRNA COVID-19 vaccination - PubMed doi: 10.1111/jdv.12942, 13. government site. doi: 10.12998/wjcc.v5.i6.203, 6. Within two weeks of topical betamethasone dipropionate treatment, the lesions disappeared completely. McMahon DE, Kovarik CL, Damsky W, et al.. Clinical and pathologic correlation of cutaneous COVID-19 vaccine reactions including V-REPP: a registry-based study. The advent of vaccines has drastically reduced the incidence, morbidity, and mortality related to COVID-19 [1]. Cazzato G, Ambrogio F, Foti C, Capuzzolo M, Trilli I, Casatta N, Lupo C, Carrieri M, Daini D, Colagrande A, Maiorano E, Ingravallo G. Diagnostics (Basel). This site needs JavaScript to work properly. It was found popularly in the trunk area, either asymptomatically or with mild symptoms. Pityriasis rosea is a common viral infection that usually affects individuals between 10-35 years of age. There are four main types of vaccines and over 240 candidate vaccines in development. Adya KA, Inamadar AC, Albadri W. Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Moles, psoriasis, hives, eczema, and recently associated Covid-19 coronavirus rashes are just a few of the more than 3,000 skin disorders known to dermatology. 2022 Aug;35(8):e15601. The site is secure. 2022 Aug;35(8):e15602. Abstract Dear Editor, Pityriasis rosea (PR) is a common, self-limited erythematous papulosquamous dermatosis that mainly affects young adults. eCollection 2023 Mar 7. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Khan I, Elsanousi AA, Shareef AM, Tebha SS, Arif A, Gul S. Immun Inflamm Dis. Disclaimer. Atypical pityriasis rosea associated with mRNA COVID-19 vaccine The cause of pityriasis rosea is not known, but it is commonly believed to be caused by a virus or bacteria. KL and KP collated resources. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). (2020) 33:e13878. Nevertheless, she did not present with fever or respiratory tract symptoms. Cutis. In 4 patients PR appeared after the first vaccination; in one patient after the second one. It manifests as oval-shaped, pink or red . HHS Vulnerability Disclosure, Help 2021 Sep;35(9):e546-e548. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Your Random Rash Could Be Pityriasis Rosea | Allure Bookshelf An official website of the United States government. Leerunyakul K, Pakornphadungsit K, Suchonwanit P. Front Med (Lausanne). *Correspondence: Poonkiat Suchonwanit, poonkiat@hotmail.com, ORCID: Kanchana Leerunyakul orcid.org/0000-0002-0669-5611Kallapan Pakornphadungsit orcid.org/0000-0003-4783-0282Poonkiat Suchonwanit orcid.org/0000-0001-9723-0563, COVID-19 Associated Cutaneous Manifestations and COVID-19 Vaccine Related Skin Reactions, View all -. Bethesda, MD 20894, Web Policies The association between pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccines was established, but given the scarcity of studies, there is a need to conduct different clinical trials to confirm this association further and study the etiology and mechanism of the disease. Pityriasis rosea after Moderna mRNA-1273 vaccine: A case series. Then you may get smaller spots that sweep out from the middle of the body in a shape that looks like drooping pine-tree branches. Veraldi S, Boneschi V, Cusini M, Maronese CA. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. Moreover, almost all lesions faded with associated post-inflammatory hyperpigmentation (Figure 2B). government site. Pityriasis rosea as a cutaneous manifestation of COVID19 infection PMC While COVID-19 vaccines offer strong and lasting protection against severe . The site is secure. Although it is known that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be associated with skin manifestations, a limited number of images are available in the literature at this time. The .gov means its official. Disclaimer. Careers. Pityriasis rosea-like cutaneous eruption as a possible dermatological manifestation after Oxford-AstraZeneca vaccine: Case report and brief literature review. NS, not specified; PR, pityriasis rosea; PRL, pityriasis rosea-like. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Epub 2021 Aug 26. and transmitted securely. In the period May 2021- February 2022 we observed five cases of clinically typical PR that appeared 2 to 3 weeks after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA- 1273 (2 patients).
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