We have absolutely no complaints of burning with our product in fact quite the opposite, which is why a large percentage of our customers use Can-C for dry eye syndrome, contact lens use and for eye strain relief. CMC) cellulose. Improved visual behavior of the mammals within weeks of treatment. Some eye drops need to be shaken before use. While generally safe and effective when used under the supervision of a veterinarian, artificial tear solutions can potentially cause side effects in some animals. Artificial tear solutions containing preservatives are available in 15 milliliter, 25 milliliter, 30 milliliter, and 0.5 and 1.0 ounce bottles. Again to be sure that you have purchased the approved formula look for the following statement on the label of any product you have purchased. Treatment of Age-Related Cataracts in Canines. Order three boxes for $105 at $35 per box . Domestic Substances List Categorization. Two weeks ago I googled cataracts in cats and found Can-C. You may report side effects to Health Canada at 1-866-234-2345. Drug interactions may change how your medications work or increase your risk for serious side effects. CMC's water solubility allows for less toxic and costly processing than with non-water-soluble binders, like the traditional polyvinylidene fluoride (PVDF), which requires toxic n-methylpyrrolidone (NMP) for processing. Q. I bought C-Can and two days later it arrived. One box of Can-C costs $39.00. A: We offer professional discounts to physicians and veterinarians so that they may supply and monitor their patients. Non-food products include products such as toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, reusable heat packs, various paper products, and also in leather crafting to help burnish edges. Ingredients have been studied extensively. Tell your doctor if your condition lasts or gets worse after 3 days. Momto3cats- thanks, I will give it a try. Refer to storage information printed on the package. It relieves irritation and discomfort caused by the dryness in the eyes. In an article onLiveStrong.com, it says that carboxymethylcellulose is not really harmful in small amounts. Because it is widely regarded as harmless, it is often used as a filling agent in the manufacture of medical pills. What to Know, Did Clifford have puppies? I just have to saymy foals eyes are clearing up at an incredible rate! Sec. Tips and Tricks, Is beef better for dogs? Generally use of this natural anti-oxidant formulation is soothing and improves the overall environment in the eye. The vet had told us that Mario (our cat) had a cataract in his eye last year. (a) Product. As for the Europe Sodium CarboxyMethyl Cellulose (CMC) landscape, Germany is projected to reach USD million by 2028 trailing a CAGR of Percent over the forecast period. A: In animals, the cataract is very visible to our view. I am so happy that I was internet surfing and looking for cataract info in horses! Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Keep in mind that the use of any unapproved drug for your animals should also be discussed with your veterinarian. [19] Skin testing is believed to be a useful diagnostic tool for this purpose. On the other hand, it can also be found in non-food items, such as K-Y jelly, toothpaste, laxatives, hand cream, antacids, diet pills, water-based paints, detergents, different paper products, artificial tears, and in laundry detergents. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. Please contact me at: robert@catcataracts.com. Carboxymethyl Cellulose is used to treat dry eyes. Thursday, December 07, 2017 by Michelle Simmons, http://www.naturalpedia.com/carboxymethylcellulose-toxicity-side-effects-diseases-and-environmental-impacts.html. Is sodium carboxymethylcellulose poisonous? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. (a) Product. Mario loves to sing and play he is about 11 years old. Optimal results are achieved with 6 12 months use. Carboxymethylcellulose may adversely affect the digestive and integumentary systems. The duration and frequency of application depends on the severity of the condition, the desired degree of lubrication and the development of any adverse effects. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. United States Pharmacopeia (USP) Reference Standard. Be sure you know if you need to avoid wearing contact lenses 2005 - 2023 WebMD LLC, an Internet Brands company. If you think there has been an overdose, call your poison control center or get medical care right away. This compound is similar to cellulose, but is also very soluble in water. I cant wait to show my vet! Other common uses of CBD for which there is at least some supportive scientific evidence (in people or non-feline animal models) include inflammatory conditionslike inflammatory bowel diseaseas well as asthma, anxiety, pain and nausea. If using an ointment once a day, it may be best to use it at bedtime. Common food additive linked to colon cancer and intestinal inflammation, Common food additives found to trigger colon cancer, study finds. Call your doctor or get medical Truth Publishing International, LTD. is not responsible for content written by contributing authors. Interestingly the eyes of those suffering from degenerative ocular diseases such as cataracts were found to be grossly deficient in this essential ocular antioxidant. Canadian Environmental Protection Act (CEPA) Environmental Registry. In the absence of data, the FEEDAP Panel was not in the position to conclude on the safety of microcrystalline cellulose for the user. Carboxymethyl cellulose ( CMC) or cellulose gum [2] is a cellulose derivative with carboxymethyl groups (-CH 2 -COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone. US residents can call their local poison control center at 1-800-222-1222. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Critical antioxidant supplies are continually being tapped from the eye, for protection against over exposure to ultraviolet light and against toxins and chemicals. The research with mammals as subjects is indisputable: Vision improves in most cases. Otherwise, call a poison control center right away. PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE, Subpart B - Multiple Purpose GRAS Food Substances. Tell all of your health care providers that you take carboxymethylcellulose. Shipping to destinations outside the US is $6.95.Click on the link below to order using any major credit card or paypal: Order two boxes for $39.00 per box or $78.00 for two boxes containing four 5 ml vial (two in each box). Product Overview Viralys is a highly palatable supplement formulated to support a healthy immune system and recommended for conditions responsive to L-Lysine. Check the label to see if you should shake your product before using. The FEEDAP Panel concluded that sodium carboxymethyl cellulose is considered safe for all animal species. Can you use carboxymethylcellulose sodium eye drops on dogs? Independence America Holdings Corp. All Rights Reserved, Uses of Artificial Tear Solutions for Dogs and Cats, Artificial Tears for Pets: Precautions and Side Effects, Dosage Information of Artificial Tears for Dogs and Cats. A very serious allergic reaction to this drug is rare. [16], Aqueous solutions of CMC have also been used to disperse carbon nanotubes, where the long CMC molecules are thought to wrap around the nanotubes, allowing them to be dispersed in water. Q. For an ointment, hold the tube directly over the eye and gently squeeze a small strip (one-fourth of an inch or roughly 6 millimeters) of ointment into the pouch. Improved visual behavior of the mammals within weeks of treatment. It is not intended as a substitute for professional advice of any kind. [10], CMC is used to achieve tartrate or cold stability in wine, an innovation that may save megawatts of electricity used to chill wine in warm climates. [12][full citation needed], CMC powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt ice mixes. The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature. Carboxymethylcellulose is made from cellulose and is used as a thickening agent, filler in foods, dietary fiber, anti-clumping agent, and emulsifier. It is the incorrect balance of PH that can result in burning with some ocular formulations and not the preservative. Q. I saw another N-Acetyl-carnosine website and they said that the preservative Benzyl Alcohol is not good, is that true? Call your doctor for medical This document does not contain all possible drug interactions. It helps in the management of irritation & dryness of the eye, Chronic Conjunctival irritation, Kerato Conjunctivitis Sicca - KCS, and Discomfort due to wind, sun, or pollution effects. Medically reviewed by Drugs.com. Read all information given to you. However, Can-C is not approved by the FDA for the treatment of dog cataracts. [15], CMC is also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice. Sodium carboxymethylcellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl groups per anhydroglucose unit, and with a minimum viscosity of 25 centipoises for 2 percent by weight aqueous solution at 25 deg.C. These studies produced remarkably fast results in the improvement of clarity and overall vision for the animals involved. Recent studies indicate that CBD can help relieve pain and promote activity in dogs with osteoarthritis and can reduce seizure frequency in cases of severe epilepsy. Pharmaceutical precautions / Instructions: Not for human use. Do not start, stop, or change the dose of any drug without checking with your doctor. If you have any questions, ask your doctor or pharmacist. An artificial tear solution, commonly known asRefresh and many other brand names,is a wetting agent used to treat keratoconjunctivitis sicca (KCS), also known as dry eye, for dogs and cats. Questions Answered and Orders: 1-877-526-4646 (Toll Free). I will be really greatful if you reply to this ! This medicine may be harmful if swallowed. However, in some patients, Carboxymethylcellulose may cause eye irritation (burning and discomfort), eye pain, itchy eyes and visual disturbance. Tell your doctor right away if you have any serious side effects, including: eye pain, change in vision, continued eye redness/irritation. [18][non-primary source needed], While thought to be uncommon, case reports of severe reactions to carboxymethyl cellulose exist. [citation needed] CMC is desirable because the catalysis product (glucose) is easily measured using a reducing sugar assay, such as 3,5-dinitrosalicylic acid. Mario is definitely out of pain! Those who are claiming that benzyl alcohol causes burning do not understand the importance of the critical PH balance of ocular formulations. [5] Fabrics made of cellulosee.g. Mammals with both immature and ripe cataracts showed significant visual improvement. My cat is white which probably makes him easy to see, but he was at least 20-30 yards away. Drug class: Ophthalmic lubricants and irrigations. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Research studies report that 96% of canine eyes treated with N-acetylcarnosine (Can-C) showed notable improvements. This is especially concerning for cats because of their increased sensitivity to medications and toxins. Natural cellulose is the most widely distributed and most abundant polysaccharide in nature, and its sources are very rich. My cats cataracts are a result of diabetes. The testing of various anti-glycation agents over nearly a decade led a Russian research team to the development of N-Acetyl-carnosine as a delivery system for the natural ocular anti-oxidant L-carnosine. Those who had cataracts for more than 15 years experienced less dramatic improvements. Brand names: Artificial Tears, Biolle Gel Tears, Biolle Tears, GenTeal, Lubricating Plus Eye Drops, We just started the 3rd bottle and for the past 3 weeks we have noticed her eyes clearing and most importantly our foal can see! However, consuming large amounts of cellulose gum may add bulk to feces and may have a slight laxative effect. CARBOXYMETHYL-2-HYDROXYETHYL ETHER SODIUM SALT CELLULOSE, CELLULOSE, CARBOXYMETHYL-2-HYDROXYETHYL ETHER, SODIUM SALT, SODIUM CARBOXYMETHYL HYDROXYETHYLCELLULOSE, SODIUM SALT CELLULOSE, CARBOXYMETHYL-2-HYDROXYETHYL ETHER, Big Market for Black Cosmetics, but Less-Hazardous Choices Limited, K-Beauty Trends: Serums, Essences and EWGs Best Bets, FDA Asks Women To Protect Themselves From Products The Agency Refused To Ban, Study Highlights Importance of Cosmetics Ingredient Safety Tests, Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product, 0 studies in PubMed science library may include information on the toxicity of this chemical, Designated as safe for general or specific, limited use in food, Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any, Not suspected to be an environmental toxin, Environment Canada Domestic Substance List, Classified as not expected to be potentially toxic or harmful. lithium ion batteries), especially with graphite anodes. I can assure you if I ever get cataracts myself or if I have another animal with them, I will also use Can C. My foal will be on maintenance with Can C all of her life. Reduce the inflammation. You will need to talk about any risks to your baby. A Complete Guide, How do Mongolians bury their dogs? about 9 out of 10 cases so odds are in your favor. In veterinary medicine, CMC is used in abdominal surgeries in large animals, particularly horses, to prevent the formation of bowel adhesions. It has also been given to cats medicinally with no problems that I've heard of. I am really worried about his eyes . A: If the cataract is advanced to the point of total blindness the results are likely to be less than a 100% reversal with the use of Can-C. Cataracts at this stage often have hardened significantly and are more resistant to the good effects of Can-C. Once cataracts have reached this advanced stage they become a constant irritant to the animal. If these drops give me a few more years of riding him, that is more than I could ask for. And he is only 8months old Fabric used as a dressing following ear nose and throat surgical procedures. [13] CMC is used in baking breads and cakes. One study tested CBD products and found that many have littleif anyCBD. Is there a need to use a syringe for injecting the solution into my cats eyes? The global key . Note: If you need help accessing information in different file formats, see help if you have any side effects that bother you or do not go away. Consistency of application is even more critical to success in the above mentioned scenarios and can mean the difference between minimal results and very good results. Use of CMC in candy preparation ensures smooth dispersion in flavor oils, and improves texture and quality. Put light pressure on the inside corner of the eye. It used to be marketed under the name Tylose, a registered trademark of SE Tylose. There are no documented drug interactions among these and other products. Heres What to Do Next, What is the best dog food you can buy? Talk to your pharmacist for more details. FDA Office of Food Safety and Applied Nutrition. It is often used as its sodium salt, sodium carboxymethyl cellulose. You can not go wrong with Can-C Eye Drops! I got fed up knowing the vet said there was nothing to do except operation which was out of the question. Will my cats cataract come back again after it has been reversed? Enter the ingredients in EWGs Build Your Own Report tool to get an approximate score for that product. Glucophage uses, health risks, and side effects at NaturalPedia.com, Norvasc uses, health risks, and side effects at NaturalPedia.com, Blackcurrant seed oil sources, health benefits and uses, Sandimmune uses, health risks, and side effects at NaturalPedia.com. When used to treat degenerative ocular conditions such as cataracts, one box will last approximately three weeks (3 drops in each affected eye daily). Certain brands (containing glycerin with polysorbates, among other ingredients) may have a milky appearance. Do the newer cataracts have a better success rate with this product? Can-Cis not FDA approved for the treatment of cataracts as the clinical trials have been conducted primarily in Russia over the last decade; therefore N-Acetyl-carnosine (1%) is listed as an inactive ingredient on the label. Research on dogs and humans show it works for What Evidence Exists that Can-C Eye Drops are Effective for Reversing Cataracts? Some people report that their pets become sleepy or develop upset tummies, particularly when given very high doses, but these problems resolve when CBD is discontinued or the dose is lowered. Talk to an experienced veterinarian. She watches our Tom cat run across the corral and her head raises as he climbs trees!! Once the eye abnormalities have been resolved, this dosage can be reduced to one drop a day. All of these indicators will clearly let you know that the product is working. Carboxymethylcellulose is particularly used as a thickening agent, but it is also used as a filler, dietary fiber, anti-clumping agent, and emulsifier. Approved by Innovative Vision Products.. It is more stable than metatartaric acid and is very effective in inhibiting tartrate precipitation. In general, the contact time of these solutions with the surface of the eye is extremely short (just a few minutes), so severe dry eye may require applications as frequently as every 1 to 4 hours. Look for the following statement on any box you purchase to be sure you are purchasing Dr. Babizhayevs patent protected formula. Carboxymethylcellulose can also be identifiedvia its alternate names, such as cellulose gum, carboxymethyl cellulose, sodium carboxymethyl cellulose, CMC, modified cellulose, and cellulose gel, and it has an E number of E466. Shipping to destinations outside the US costs $6.95. After you apply this product, your vision may become temporarily blurred. [20] CMC is often used in conjunction with styrene-butadiene rubber (SBR) for electrodes requiring extra flexibility, e.g. And how many drops should i apply on his eyes ? This medication is used to relieve dry, irritated eyes. Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation, Carboxymethyl Hydroxyethylcellulose is an ethylene glycol ether of Cellulose Gum (q.v.). Do this for 1 to 2 minutes. Throw away unused or expired drugs. For drops/gels, place the dropper directly over the eye and squeeze out 1 or 2 drops as needed. Before using this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This will prevent the medication from draining away from the eye. It is made from cellulose, which is the main polysaccharide and makes up the woody parts and cell walls of plants. This helps us offset the costs of running this site, so thank you for your support! This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. A. Can-C is a great solution for animals that do not have surgery as an option, and has been successfully used to treat the cataracts of domestic animals of all sizes. Put pressure on the inside corner of the eye. Shake well before use. Q. Do not share your drugs with others and do not take anyone else's drugs. Most artificial tear solutions contain preservatives but some are preservative-free. If the information is appropriate for the lead of the article, this information should also be included in the body of the article. www.catcataracts.com Sodium carboxymethylcellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl. The use of microcrystalline cellulose in animal nutrition is of no concern for consumer safety. After giving this drug, ask your child to keep eyes closed. Two months later and that film is gone from both eyes. The information on this site is provided for educational and entertainment purposes only. Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. A: With this formula, utilized in 10 years of human and animal clinical trials, there have been no reported side effects or contra-indications, even when used everyday for up to 2 years. Cellulose gum, or sodium carboxymethyl cellulose (sodium CMC), is a multi-functional ingredient that can be used as a thickener, binder, emulsifier and stabilizer in food with the European food additive number E466. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Artificial tear solutions are not approved for use in animals, but they can be used in an extra-label manner. I want to try this eyedrop on him ! About TheCatSite.com. [21], Except where otherwise noted, data are given for materials in their. All Rights Reserved. Cross linking of the lens proteins eventually causes a yellowing or browning pigmentation of the lens or (lens opacification) limiting the amount of light that reaches the retina, resulting in worsening vision. The dropper tip should not be touched to any surface as this can contaminate the solution. Blurring of vision Carboxymethyl Cellulose may cause short-term blurring of vision, pain/irritation/discomfort in the eyes. Usually, drops may be used as often as needed. This unchecked oxidation results in the cross linking of lens proteins, which is a slow glycosylation process. Those who had cataracts for seven to 15 years still received very good results. This keeps the drug in your Do not start, stop, or change the dosage of any medicines without your doctor's approval. 1, No. Interestingly it was the formulation with the preservative benzyl alcohol in combination with a unique source and purity level of NAC. If you choose to try CBD for your cat, here are a few ways that you can protect your pets from poor-quality CBD: Find products that carry the Certified Seal of the U.S. Hemp Authority or the National Animal Supplements Council (NASC) Quality Seal, as these meet industry-imposed standards and have passed a third-party audit. for use with silicon-containing anodes. No, Carboxymethylcellulose is a safe medicine. This page was last edited on 18 April 2023, at 03:22. Be sure you know if this product needs to be shaken before using it. Together with xanthan gum, they're the most used and common thickener among others in food applications. Carboxymethylcellulose Sodium 0.5 % Eye Drops Artificial Tear Solution Carboxymethylcellulose Sodium 0.5 % Eye Drops Artificial Tear Solution - Uses, Side Effects, and More Generic Name (S):. People with liver or kidney problems may need lower doses. [citation needed], Following the initial reaction, the resultant mixture produces approximately 60% CMC and 40% salts (sodium chloride and sodium glycolate); this product is the so-called technical CMC, which is used in detergents. Also, minor burning/stinging/irritation may temporarily occur. CMC has been used in various medical applications. It is calculated using a weight-of-evidence . Like other modified celluloses, cross-linked sodium carboxymethyl cellulose is considered to be of, How do you bond with baby and dog? Tagged Under: Tags: Carboxymethylcellulose. Normal storage in a cool; dry and dark place. Does Carboxymethylcellulose Sodium 0.5 % Eye Drops Artificial Tear Solution interact with other drugs you are taking? Keep all medications away from children and pets. Description / Action: LIGHTSENSE COOL is a Carboxymethyl Cellulose Sodium Eye Drop for dogs and cats. Artificial tear solutions should not be used in animals with known hypersensitivity or allergy to the drug. Do you know if any of the ingredients are potential allergens? [citation needed], CMC is sometimes used as an electrode binder in advanced battery applications (i.e. Click on the link below to order using any major credit card or Paypal. We ship Can-C to all countries in the world! If you notice other effects not listed above, contact your doctor or pharmacist. If you use carboxymethylcellulose on a regular basis, use a missed dose as soon as you think about it. Improvement in your cats behavior and negotiation abilities is generally a good indicator of the desired result being achieved. This can cause chronic inflammation of the eye, which may result in a decrease in vision. Surgery on your cats cataracts is obviously an option, but consider the safe alternative. When used as a preventive or maintenance measure, only one drop in each eye daily is needed so one box of Can-C will last many weeks longer. The various types of artificial tear solutions commercially available attempt to mimic the normal corneal tear film, and to replace components of the natural tear film. Applying the Can-C eye drops to your cats eyes three times a day does not involve the risk of surgical complications or side effects. Do not flush down a toilet or pour down a drain unless you are told to do so. Food preservatives and chemical additives found to promote obesity is this why America is so overweight? His eye is looking better every day. It is also important to note, that legally, a hemp plant cannot contain more than 0.3% THC or else it is considered a Schedule I controlled substance (illegal narcotic). Surprising Answer. It is used primarily because it has high viscosity, is nontoxic, and is generally considered to be hypoallergenic, as the major source fiber is either softwood pulp or cotton linter. Carboxymethylcellulose is made from cellulose and is used as a thickening agent, filler in foods, dietary fiber, anti-clumping agent, and emulsifier. While CBD is present in all cannabis plants, its primarily derived from the hemp plantwhich a recent study defines as, Cannabis sativa with a total THC (tetrahydrocannabinol) less than 0.3% dry weight in leaves and buds.. Other names for carboxymethylcellulose include cellulose gum, carboxymethyl cellulose, sodium carboxymethyl cellulose, CMC, modified cellulose, cellulose gel, and E466. [17] Carboxymethyl cellulose is suggested as a possible cause of inflammation of the gut, through alteration of the human gastrointestinal microbiota, and has been suggested as a triggering factor in inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Firstly, it is now known that cataract is the result of elevating levels of ascorbate oxidation or oxidative stress due in part to oxygen free radicals in the eye. I also had to rescue my cat (yes the one with the cataract) from my horse because he decided to chase him out of the paddock the other day not not something he has done in so long I cant remember the last time! It may be labeled as a dietary fiber on the packaging of food products, but the Center for Science in the Public Interest warns that cellulose gum or carboxymethylcellulose is not as healthy as the fiber found in natural foods. calcified. cyclosporine ophthalmic, Restasis, varenicline, Xiidra, Artificial Tears, Systane. Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications.This product may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, hypromellose, polyethylene glycol 400 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others.Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye. Tell your doctor if you are pregnant or plan on getting pregnant. I have my degree in Animal Nutrition/Horticulture so I am cautious what I give to our animals when they are not well. Tear deficiency is caused by reduced production of the aqueous layer of the tear film, which causes quantitative tear deficiency and leads to inflammation of the Conjunctiva and Cornea known as Keratoconjunctivitis Sicca (KCS), or Dry Eye. TheCatSite.com is a community of cat lovers dedicated to quality cat care and cat welfare. It is meant for external use only and is not harmful. Benzyl alcohol has long been utilized in ocular formulations as an FDA approved preservative. It is believed that preservative-free solutions may be milder and cause less irritation of the cornea, particularly with long-term administration. [8], Insoluble micro granular CMC is used as a cation-exchange resin in ion-exchange chromatography for the purification of proteins. Carboxymethylcellulose may have a laxative effect and may cause digestive problems, such as flatulence, diarrhea, and cramping, when consumed in large amounts. Dr. Babizhayev has also noted that Can-C appears to work even more effectively in animals than in humans.
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